Home Work
second task
Integrated gene-finding programs begin by searching for signals
and performing a coding region analysis. The scientists attempt
to define exons and give one or more tentative gene structures
that seem most consistent with all the data at hand. Several such
integrated algorithms are now available, and can give a good idea
of gene structure in at least some circumstances.
1. Please download the DNA sequence of the
human enolase gene (accession number X56832) from GenBank.
2. Look at the annotation part. How
many coding sequences (CDs) are there in this sequence? Please
identify the position of each CD.
3. Go to http://gnomic.stanford.edu/~chris/GENSCANW.html
4. Predict the position and length of
the exons with GENSCAN.
5. Compare the results of annotated
exons from the GenBank report and predicted the exons from
GENSCAN. Show all results on your homepage.